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Reducing LDL of 'bad' cholesterol is central to reducing cardio vascular risk. While the mainstay of doing this is dietary interventions and medication, there are some supplements which are backed by science and can contribute. 

Dietary and Lifestyle changes required are detailed in these videos

It is important that LDL is treated to target. Speak to your physician about your treatment target and ensure that LDL or 'bad' cholesterol is monitored to ensure that this is at or below target. 

  1. Omega 3:

Fish and seafood are good food sources of Omega-3, but this can be supplemented as well. It is reasonable to start with one capsule once a day with food and titrate up in consultation with a treating physician based upon biomarkers such as triglycerides, HDL, and hs-CRP in conjunction with lifestyle and dietary changes.

Vegan Option: 

 

Click to Read Scientific Study

 

2. Prebiotic Fibre :

Nutrients which gut microbiome requires as food or 'prebiotics' include fibre ( soluble fibre, insoluble fibre, resistant starch etc ), plant polyphenols, omega 3 and plant proteins. While these can be obtained from diet, supplements can also provide these dietary nutrients . Fibre reduces cholesterol, reduces sugar, improves metabolism by feeding gut microbiome and provides satiety through bulking effects. 

Dietary Sources: Whole grains, fruits, vegetables, legumes, and nuts. Green banana flour contains a high amount of resistant starch.

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Click to Explore PURICA Fiberlicious Inulin Powder 800g, 89 Servings, Pure Chicory Root Extract, Prebiotic Dietary Fibre for Daily Wellness, Easily Dissolves in Water, Ideal for Smoothies & Baking, Vegan & Gluten-Free

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Click to buy on Amazon: Metamucil, Daily Psyllium Husk Powder Supplement

 

Click to read study demonstrating benefits of Green Banana Resistant Starch for Fatty Liver

Click to read study published in Science Direct

Click to read study published in Nutrition Journal

 

3. Probiotics: This Probiotic has shown reduction in cholesterol in scientific studies through remodelling the gut microbiome and lipid metabolism in a positive way

Brand: PURICA Probiotic Cardio Formula, 30 Vegan Capsules - Digestive Balance & Immune System Boost - Dietary Supplement for Men & Women

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Click to buy on Amazon-Canadian

Click to read study published in Cambridge University Press

Gut microbiome is modulated positively by 

  • Increased consumption of:
    • Fermented Foods
    • Fibre
    • Plant proteins
  • And reduced consumption of:
    • Refined sugars
    • Saturated Fats
    • Ultra processed foods

 

4. Probiotics for Weight Reduction

Brand: Genestra Brands HMF Metabolic | Probiotic Formula

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Click to buy on Amazon-Canadian

Click to read Scientific Study published in journal Nature

 

Brand: Metagenics - UltraFlora Control - 30 Capsules

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Click to buy on Amazon

Click to read Scientific study published in journal Lancet

 

5. Berberine: This is a herb which stimulates AMP Kinase and reduces insulin resistance. It also has benefits for weight loss and lipid control. It also has anti inflammatory and anti oxidant properties. Berberine aids in weight loss via various mechanisms including Gut microbiome modulationDose of berberine is one 500 mg capsule thrice a day with meals ( 1.5 gms per day ) 

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Click to Explore Organika Berberine - High Potency, Cholesterol and Glucose Metabolism Support, Helps Maintain Cardiovascular Health - 60vcaps-Canadian

Click here to read study published in Science Direct

 

7. Probiotics for Fatty Liver

Certain Probiotics have also demonstrated benefit for Liver Health. While the scientific evidence to back these probiotics appears promising, further study is required to confirm these claims. Most of the studies were conducted by the companies themselves, which introduces a risk of bias within the results.

Brand: Culturelle Healthy Metabolism, Helps Maintain a Healthy Metabolism and Supports Good Health

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Click to buy on Amazon

Click to read study published in Hepatology & Nutrition

 

Brand: Visbiome High Potency Probiotics, 112.5 Billion CFU Live, 60 Caps

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Click to buy on Amazon

Amazon Link for USA

Click to read study published in British Medical Journal for Fatty Liver